IVF therapy is likely one of the most typical therapy strategies for individuals who need to have a child. There are new developments within the discipline of IVF purposes day by day. Frozen embryo switch is likely one of the exceptional purposes. How does frozen embryo switch have an effect on the probabilities of success in IVF? Which examinations and checks must be completed earlier than beginning IVF therapy? How does hydrosalpinx (fluid assortment in tubes) have an effect on the prospect of being pregnant and the way is it handled? What does low AMH (anti-mullerian hormone) worth imply? What’s a cracking needle, what’s it for, how does it work?
Istanbul IVF and Ladies’s Well being Heart Ladies’s Well being and IVF Specialist Op. Dr. Modern Lion answered all questions in All the pieces For My Well being
Frozen embryo switch is likely one of the most curious matters. How does it have an effect on the probabilities of success in IVF purposes, are you able to give detailed info on this topic?
“Probably the most essential current developments in IVF applied sciences is the development in embryo freezing. Now that we are able to freeze embryos higher, their survival price after thawing has reached a lot increased ranges.
When frozen embryo switch is carried out in an acceptable affected person group, it positively will increase the opportunity of being pregnant. For instance, dozens of eggs of a polycystic ovary affected person had been collected. Consequently, it is in a hormonal storm. While you switch the embryo to the affected person earlier than this hormonal storm stops, we scale back the opportunity of being pregnant. While you freeze their embryos, look ahead to the top of this hormonal storm after which switch, we positively improve the prospect of the affected person to conceive.
Alternatively, typically in sufferers the place progesterone hormone rises early, our embryo transfers might fail as a result of the internal tissue of the uterus is incompatible with the embryo. Freezing the embryo and suspending the switch to the following month makes the outcomes we obtain way more passable in sufferers the place we discover this excessive progesterone top. In brief, when frozen embryo switch is made to the affected person, it will increase the opportunity of being pregnant. ”
TREATMENT SHOULD START WITH THE ASSESSMENT OF WOMEN AND MEN TOGETHER
Which examinations and checks must be completed earlier than the IVF therapy?
“IVF therapy ought to begin with the analysis of the girl and the person collectively. To begin with, the situation of the uterus and ovaries must be evaluated with the ultrasound carried out on the girl. Then, the uterine movie must be requested from the girl with a view to distinguish the deformities of the uterus and tubes and potential obstructions within the tubes. Uterine X-ray is the least dangerous, best method to consider tubes. Doable issues within the tubes can instantly forestall the affected person from getting pregnant. Due to this fact, evaluating the tubes is essential within the first analysis of the affected person.
Once more, blood checks that can examine whether or not conception of a lady will hurt her personal well being, in addition to analysis of hormones that can trigger abortion, equivalent to thyroid hormones, are indispensable checks for the girl on the first examination.
Alternatively, the analysis of the 2 sperm checks of the person, which is completed each two weeks, will forestall any misunderstandings and misinterpretations. “
“LIQUID COLLECTION IN TUBES CAN PREVENT PREGNANCY”
You have got emphasised the significance of tubes. For instance, how does Hydrosalpinx (fluid assortment in tubes) have an effect on the prospect of being pregnant?
“One of many organs that must be evaluated particularly earlier than beginning IVF therapy is the tubes of the uterus. Fluid accumulation issues within the tubes can forestall the affected person from conceiving by himself, and should trigger miscarriage within the early weeks.
If the tubes are blocked at any degree, it causes fluid to build up in them on account of their very own secretions. Usually, the tubes take away their fluids and pour them into the stomach, the place this fluid is absorbed. However when the tube is clogged, there is just one space the place the tube can pour its liquid; it is usually contained in the womb. Due to this fact, in a switch you make, even when the embryo you transferred has 100 cells, the 3-5 cc, 3-5 mm liquid gathered in that tube will act as when you poured a bucket of liquid on the embryo and wash the embryo and throw it out of the uterus. On the identical time, these fluids that accumulate within the tubes can create poisonous substances in them and trigger the termination of being pregnant even when you conceived within the early weeks. Due to this fact, this can be very essential to judge the uterine tubes earlier than therapy in IVF remedies. “
“A LOW OF AMH DOES NOT INDICATE THAT YOU CAN-BE A MOM”
“Hormones are additionally essential. What does low AMH (anti-mullerian hormone) worth imply? “
“The anti-mullerian hormone with the medical title AMH is a biochemical indicator of what number of eggs are within the ovary. A low AMH, roughly beneath 1 AMH, signifies that there are fewer eggs in your ovary than anticipated. Nevertheless, low AMH doesn’t point out whether or not anybody can turn into a mom. It doesn’t give any details about the standard of your egg in your ovary. So what ought to I do if AMH is low? If AMH is low, I’ve to remember that I haven’t got many eggs. As quickly as I’m planning a toddler, I’ve to take motion on this. If I can not get pregnant alone, I must go to the specialist of this enterprise and be examined. No, if I’m not married, I’ve low AMH and if I need to have kids sooner or later, I must analysis egg freezing choices and repair this downside. “
.Fracturing needle can be probably the most curious matters. What’s a cracking needle, what’s it for, how does it work?
“Cracking needle, as it’s popularly identified, is definitely the needle we use to ripen the eggs. Cracking is a misspelled title. Usually, we observe the fluid-filled sacs we name follicles with ultrasound. The egg stays hooked up to the wall of those sacs earlier than the cracking needle is made. After we make the fracturing needle to the affected person as it’s popularly identified, about 36 hours later, that egg breaks off the wall and falls into the liquid-filled sac that I discussed. Within the egg assortment course of, we drain this liquid and ship the embryo underneath the microscope. When examined underneath the microscope, the embryologist finds the ovary and provides us an egg. Therefore the cracking pin just isn’t like its title. It is really a maturation needle. It doesn’t crack the egg, it tears the egg from the wall and falls into the follicle fluid, thus permitting us to advance the therapy. ”
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